[ver.2.o]
S. No. |
Title |
In class discussion | Due date |
Form of submission |
Date posted |
Additional Information | Assessment | Solution |
1 | Critical reading and order of magnitude estimates: What is Galieo's point about giants? | XX-09-2021 | 20-09-2021 | 17-August: prepare to discussbased on the previously shared slides
and handout materia.
19-Agust: Upload assignment in GoogleClassroom |
19-Aug | Use any source from the internet, published literature, books etc. | 10 pts: In class responses will be separately
evaluated.
10 pts: Written reports will be separately evaluated |
|
2 | Python code running examples | 6-Sep | 13-Sep | Run the example codes given and discuss any problems in class | 13-Sep | Use online help files and other resources. Should be your own work. | 10 points for in class discussion | |
2 | Simulating the flipping of a fair coin | 20-Sep | 20-Sep | Write code in Python to simulate the flipping of a fair coin
The code should take an input from the user to determine the number of coin flips (more than 1). Then, using a random number generator the code should generate random choices between heads and tails, and store the outcome in a "list" object. Code should be uploaded before class on the classroom site. |
20-Sep | Use the uploade example script as a help. | 15 points for code running as expected. Bonus points for originality. | |
3 | Simulating the binomial segregation of proteins into daughter cells | 27-Sep: discussing the problem | 1-Oct | Upload ipython code in the GoogleClassroom environment of the BIO315
course.
In class discussion with T.A. (TBA) |
Ref.: Rosenfeld N, Young JW, Alon U, Swain PS, Elowitz MB (2005) Gene regulation at the single-cell level. Science 307:1962-1965. | 1. Does the code run without an error
2. Does it perform the calculations required 3. Does it plot the variables as expected, with axes labelled 20 points |
||
4 | Critical reading: Measuring mechanics of cytoskeletal filaments | 11-Oct in class figure-wise discussion of paper
15-Oct: Written submission uploaded to g-classroom. |
Reading:
Written submission: Oct |
(A) In class discussion Oct Paper on torsion
viscometry
of cytoskeletal proteins to understand (a) Principle of experiment, (b) nature of setup (parts) and (c) conclusions. REF: Janmey (1991) A torsion pendulum for measurement of the viscoelasticity of biopolymers and its application to actin networks J. Biochem. Biophys. Meth. 22:41 (B) Written submission after class (Due: Oct) submission for paper reading assignment- Janmey 1991" The report should have the following format: (a) Title (b) Principle of experiment, (c) nature of setup (parts) and (d) conclusions. Please write in your own words. The report will be passed through a plagiarism checker. Marks will be awarded to the group and become the score of each member of the group too. example). The group members should be clearly listed on the top of the page |
9/9/2018 | REF: Janmey (1991) A
torsion pendulum for measurement of the viscoelasticity of biopolymers and its application to actin networks J. Biochem. Biophys. Meth. 22:41 [PDF] |
In class explanation of individual figures: 15 marks
Report submission: 15 marks |
|
5 | Critical reading & presentation (group activity) | None (related to imaging, resolution and magnification) | Presentations on 8-Nov-2020 | Presentation with slides and board-work to demonstrate:
1) Principle of functioning of the system 2) Application of the method to specific biological problem 3) Advantages and disadvantages of the method |
19-Aug-2020 |
|
||
6 | FCS Perpsective: Maiti S, Haupts U, Webb W W (1997) Proc Natl Acad Sci USA 94:11753–11757, pmid:9342306. |
15-Nov-2020 | 15-Nov-2020 | In class discussion of figures and equations.
Evaluation based on: 1) explanation of figures
2) connection with theory 3) understanding of the perpsective article |
19-Aug-2020 | REF (pdf): http://www.pnas.org/content/pnas/94/22/11753.full.pdf | In class explanation of individual figures: 15 marks | |
7 | Critical reading: Affinity Chromatography | 5-Dec-2020 | 5-Dec-2020 | In class discussion of figures and equation. Evaluation based on:
|
19-Aug-2020 | Kasai and Ishii (1975) Quantitative Analysis of Affinity Chromatography of Trypsin: A New Technique for Investigation of Protein-ligand Interaction.J Biochem. 77, p261-264. | In class explanation of individual figures: 15 marks | |