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Histone acetyltransferase p300 (p300 HAT) infosheet
UniprotKB AccessionQ09472
Alternative Name(s)E1A-associated protein p300
Writer for PTM/s H3K27ac, H3K56ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac, H3K18ac
EC number 2.3.1.48
No. of coding genesHistone acetyltransferase p300 is coded by following 1 non-allelic gene/s
Gene nameE1A binding protein p300
Gene symbolEP300
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s
Aliasesp300, KAT3B
GeneID2033
Chromosomal location22q13.2
HGNC3373
UnigeneHs.517517
MIM602700
RefSeq mRNANM_001429.3
RefSeq ProteinNP_001420.2
Disease associations
Cancer: Leukemia; PMID: 10700188
Cancer: Breast cancer; PMID: 10700188
Cancer: Pancreatic carcinoma; PMID: 10700188
Cancer: Colorectal cancer; PMID: 10700188
Cancer: Colorectal cancer; PMID: 8622873
Cancer: Gastric cancer; PMID: 8622873
Cancer: Cervical cancer; PMID: 11181085
Developmental disorder: RTS (Rubinstein- Taybi syndrome); PMID: 15706485