Open Positions

January4

PhD, intPHD candidates and Postdoctoral Fellows

Current openings:

Opportunities in my lab in 2020-August-PhD, iPhD and postdoc.

1. Motivated  PhD, integrated PhD & iPhD candidates (Biology, Physics and related subjects) interested in Working on Collective motor driven microtubule (MT) transport and MT  dynamics. Work can involve either of the approaches: (a) Computer Simulations or (b) in vitro reconstitution (biochemistry+microscopy). (c) We are also looking for people to join us who want to learn how to use Microfluidics for bacterial cell biology using a lab-on-chip approach and computational modeling of Bacterial Cytoskeletal Systems.

In case of interest in any of these projects, email me with your interest and motivation.

PHD SELECTIONS 2022-August Intake Details on the IISER Pune main page:

http://www.iiserpune.ac.in/admissions/phd-programme/phdadmissionbio

Last date to apply: TBA


2. Postdoctoral candidates [CURRENT opening: Email in case of interest]

(A) Computational Cell Biology (Simulations): As part of an ongoing project funded by the Indo-French Centre for Promotion of Advanced Research (CEFIPRA) we have ONE POSTDOCTORAL POSITION open. The project involves developing a computational model of the dynamics of spindle assembly. The proposed work will involve both computer simulations of Microtubule-Motor transport and mechanics as well as data analysis and comparison to large experimental data sets obtained from microscopy. Our French collaborator Dr. Marie Delattre in ENS Lyon has developed some insight into the evolutionary diversification of mitotic spindles. The project aims to address these from a theoretical perspective.

The potential candidate should have experience in simulations in computational biology. The work involves the use of C/C++ programming and Python for data analysis. It also involves the need to have an interest in or previous experience with protein dynamics and mechanics.

(B) National Postdoctoral Fellows (NPDF): The SERB funded support for a postdoctoral experience in the lab could be either in computer simulations of Microtubule-Motor systems, or the purification of novel tubulins (experimental biochemistry and microscopy).


3. We are currently NOT hiring semester trainees or interns.

4. Summer trainees are taken through the institute’s central Summer Research Fellowship programme.


PhD and integrated PhD candidates

If you are interested in spatial patterns at the cellular scale using experimental or theoretical methods, then come talk to us. 

If you are interested in quantitative cell biology and experimental and theoretical biophysics at the cellular scale, come talk to me.
Current projects on offer:
Experimental projects
  • How do microtubules determine organelle positioning like nuclear positioning during mitosis in Saccharomyces cerevisiae?
  • What is the role of cortical motors and drag-forces of the cytoplasm in C. elegans spindle mechanics?
  • What is the balance of forces in spindle alignment and positioning in embryonic divisions during mitosis?
  • Can we reconcile theory and experiment of collective Microtubule-Motor driven transport?
  • Microfluidics for a Lab-on-Chip approach to understanding (a) MT-motor systems and (b) bacterial cell morphogenesis

Your qualifications:
Experimental projects require a Masters or equivalent in Biochemistry, Molecular Biology, Microbiology, Zoology, Botany, Physics, BioEngineering, Quantitative Biology, Systems Biology or Biophysics with some experience in protein biochemistry or microbial culture. IISER BS-MS graduates interested are encouraged to apply, independent of stream.

Theoretical projects require a Masters or equivalent (B.E./B.Tech etc) in bioinformatics, biotechnology, bioengineering, biophysics, computer science or theoretical biology or an IISER P/K/M/Th/B/Tr/Bh BS-MS dual degree.

What you will do, if you choose to join us: Some lab members focus on experimental work, others on theoretical (computer simulations) work, others still on data-analysis.

PhD and iPhD student recruitment is currently possible only through IISER-Pune’s centralized entrance- the IISER PhD Programm (Aug intakes).

Methods used in the lab: Protein-biochemistry, in vitro reconstitution, fluorescence imaging, cell culture, microfluidics device integration, Monte-Carlo and Langevin dynamics simulations and computational image-anaylsis [Refer to Eils and Athale (review)]. We have a cell-culture based model system with micropatterned cells and exciting work at the interface of cell-biology, biochemistry and physical biology is being done. A project will be defined based on the lab needs and your training and interest.


Postdoctoral Candidates with a strong background in any one of the following are welcome to apply (funding by writing a grant):
  • Computational Biology
  • Cellular biophysics: cytoskeletal dynamics, cell-culture and developmental patterns
  • Lipid encapsulation of proteins
  • Cytoskeleton or molecular motor biochemistry
  • Dnamic light microscopy
  • Image analysis
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