Histone H3.2
Histone H3.2 variant expression is replication dependent (PMID: 16571659). It mostly harbours modifications that mediate transcriptional repression (PMID: 16267050). Newly synthesised H3.2 molecules are reported to undergo dynamic acetylation and methylation (PMID: 16464854).
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| UniprotKB Accession | Q71DI3 | ||
|---|---|---|---|
| Alternative Name(s) | Histone H3/m, Histone H3/o | ||
| No. of coding genes | Histone H3.2 is coded by following 3 non-allelic gene/s | ||
| Gene name | histone cluster 2, H3c | histone cluster 2, H3a | histone cluster 2, H3d |
| Gene symbol | HIST2H3C | HIST2H3A | HIST2H3D |
| Promoter region (-700 TSS +300) | Get sequence | Get sequence | Get sequence |
| Previous Symbol/s | H3F2, H3FM | ||
| Aliases | MGC9629, H3/m, H3, H3.2, H3/M | H3/n, H3/o | |
| GeneID | 126961 | 333932 | 653604 |
| Chromosomal location | 1q21.2 | 1q21.2 | 1q21.2 |
| HGNC | 20503 | 20505 | 25311 |
| Unigene | Hs.647745 | Hs.706618 | Hs.712062 |
| MIM | 142780 | ||
| RefSeq mRNA | NM_021059.2 | NM_001005464.2 | NM_001123375.2 |
| RefSeq Protein | NP_066403.2 | NP_001005464.1 | NP_001116847.1 |
| Disease associations | No disease associations known for Histone H3.2 | ||
Histone H3 variants Histone H3-like centromeric protein A, Histone H3.1, Histone H3.1t, Histone H3.2, Histone H3.3, Histone H3.3C