Histone H2A type 1

H2A type 1 gene is located in cluster 1 on chromosome number 6. On activation of angiotensin II (AngII) type 1 receptor (AT(1)R) histone isoforms H2A type A/O were found to be exchanged with isoform H2A type M (PMID: 20838438).

Click on PTM for further information Notice: Use of undefined constant extract_pos - assumed 'extract_pos' in /var/home/coee/public_html/histome/variants.php on line 60 Notice: Use of undefined constant extract_pos_mod - assumed 'extract_pos_mod' in /var/home/coee/public_html/histome/variants.php on line 61

Download table as Excel
Histone H2A type 1 (H2A.1) infosheet
UniprotKB AccessionP0C0S8
Alternative Name(s)Histone H2A/p
No. of coding genesHistone H2A type 1 is coded by following 5 non-allelic gene/s
Gene namehistone cluster 1, H2aihistone cluster 1, H2akhistone cluster 1, H2alhistone cluster 1, H2amhistone cluster 1, H2ag
Promoter region (-700 TSS +300)Get sequenceGet sequenceGet sequenceGet sequenceGet sequence
AliasesH2A/cH2A/dH2A/i, dJ193B12.9H2A/n, H2A.1pH2A/f, H2A/p, H2A.1b
Chromosomal location6p22.16p22.16p22.16p22.16p22.1
RefSeq mRNANM_003509.2NM_003510.2NM_003511.2NM_003514.2NM_021064.4
RefSeq ProteinNP_003500.1NP_003501.1NP_003502.1NP_003505.1NP_066408.1
Disease associations
CancerHepatocellular carcinoma21239733
CancerLung carcinomas6542967

Histone H2A variants Core histone macro-H2A.1, Core histone macro-H2A.2, Histone H2A type 1, Histone H2A type 1-A, Histone H2A type 1-B/E, Histone H2A type 1-C, Histone H2A type 1-D, Histone H2A type 1-H, Histone H2A type 1-J, Histone H2A type 2-A, Histone H2A type 2-B, Histone H2A type 2-C, Histone H2A type 3, Histone H2A-Bbd type 1, Histone H2A-Bbd type 2/3, Histone H2A.J, Histone H2A.V, Histone H2A.x, Histone H2A.Z