Protein arginine N-methyltransferase 7
PRMT7 is reported to catalyse the in vitro methylation of histone H2A and H4. It specifically creates symmetric dimethylarginine marks (PMID: 15494416).
| UniprotKB Accession | Q9NVM4 |
|---|---|
| Alternative Name(s) | Histone-arginine N-methyltransferase PRMT7, [Myelin basic protein]-arginine N-methyltransferase PRMT7 |
| Writer for PTM/s | |
| EC number | 2.1.1.-, 2.1.1.125, 2.1.1.126 |
| No. of coding genes | Protein arginine N-methyltransferase 7 is coded by following 1 non-allelic gene/s |
| Gene name | protein arginine methyltransferase 7 |
| Gene symbol | PRMT7 |
| Promoter region (-700 TSS +300) | Get sequence |
| Previous Symbol/s | |
| Aliases | FLJ10640, KIAA1933 |
| GeneID | 54496 |
| Chromosomal location | 16q22.1 |
| HGNC | 25557 |
| Unigene | Hs.653193 |
| MIM | 610087 |
| RefSeq mRNA | NM_019023.2 |
| RefSeq Protein | NP_061896.1 |
| Disease associations | Cancer: Breast cancer; PMID: 18293085 |
Arginine methyltransferases Histone-arginine methyltransferase CARM1, Protein arginine N-methyltransferase 1, Protein arginine N-methyltransferase 2, Protein arginine N-methyltransferase 5, Protein arginine N-methyltransferase 6, Protein arginine N-methyltransferase 7, Protein arginine N-methyltransferase 8