Histone H1.1

H1.1 expression is replication dependent. Its gene is present on cluster 1 on chromosome number 6 and mRNA is not polyadenylated (PMID: 19587527). Expressed in Hassall's corpuscles of the thymus and at a very low levels in human testis (PMID: 1626339, PMID: 9324306). There exists a rapid exchange of histone H1.1 on the chromatin fiber throughout the cell cycle (PMID: 11130728). A recent report classifies it as a weak condensor of chromatin (PMID: 19794910).

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Histone H1.1 infosheet
UniprotKB AccessionQ02539
Alternative Name(s)
No. of coding genesHistone H1.1 is coded by following 1 non-allelic gene/s
Gene namehistone cluster 1, H1a
Gene symbolHIST1H1A
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/sH1F1
Chromosomal location6p22.1
RefSeq mRNANM_005325.3
RefSeq ProteinNP_005316.1
Disease associationsNo disease associations known for Histone H1.1

Histone H1 variants Histone H1.0, Histone H1.1, Histone H1.2, Histone H1.3, Histone H1.4, Histone H1.5, Histone H1oo, Histone H1t, Histone H1x, Testis-specific H1 histone