Physics
Dr. Anjan Roy
ICTP, Trieste
Abstract: Bacterial growth requires protein synthesis. It is carried out proteins. However, being made up of protein sub-units themselves the proteins converting environmental nutrients into amino acids, but also interesting trade-off of how much of its ribosomes should it allocate to
producing more ribosomes as opposed to producing other proteins, so as to
We present a simple, mechanistic model which demonstrates this trade-off,the growth rate of the cell. Moreover, bacteria must dynamically adapt uses a simple feedback mechanism to achieve this, by dynamically driving
this allocation parameter towards the optimal value for different
environments. The resultant model is consequently capable of explaining antibiotic and other such perturbations under one unified framework.
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