Eyes absent homolog 2

EYA2 is involved in the dephosphorylation of histone H2A.X at the tyrosine 142 residue. It is involved in the DNA damage response (PMID: 19351884).

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Eyes absent homolog 2 infosheet
UniprotKB AccessionO00167
Alternative Name(s)
Eraser for PTM/s H2AY142ph
EC number
No. of coding genesEyes absent homolog 2 is coded by following 1 non-allelic gene/s
Gene nameeyes absent homolog 2 (Drosophila)
Gene symbolEYA2
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s
Chromosomal location20q13.1
RefSeq mRNANM_005244.4NM_172110.3
RefSeq ProteinNP_005235.3NP_742108.2
Disease associations
Cancer: Lung adenocarcinoma; PMID: 19950702

Serine/threonine/tyrosine phosphatases Dual specificity protein phosphatase 1, Eyes absent homolog 1, Eyes absent homolog 2, Eyes absent homolog 3, Protein phosphatase 1D, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, Serine/threonine-protein phosphatase 4 catalytic subunit, Serine/threonine-protein phosphatase 5, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit