Eyes absent homolog 3
EYA3 is involved in the dephosphorylation of histone H2A.X at the tyrosine 142 residue. It is involved in the DNA damage response (PMID: 19351884).
| UniprotKB Accession | Q99504 |
|---|---|
| Alternative Name(s) | |
| Eraser for PTM/s | H2AY142ph |
| EC number | 3.1.3.48 |
| No. of coding genes | Eyes absent homolog 3 is coded by following 1 non-allelic gene/s |
| Gene name | eyes absent homolog 3 (Drosophila) |
| Gene symbol | EYA3 |
| Promoter region (-700 TSS +300) | Get sequence |
| Previous Symbol/s | |
| Aliases | DKFZp686C132 |
| GeneID | 2140 |
| Chromosomal location | 1p36 |
| HGNC | 3521 |
| Unigene | Hs.185774 |
| MIM | 601655 |
| RefSeq mRNA | NM_001990.3 |
| RefSeq Protein | NP_001981.2 |
| Disease associations | No disease associations known for Eyes absent homolog 3 |
Serine/threonine/tyrosine phosphatases Dual specificity protein phosphatase 1, Eyes absent homolog 1, Eyes absent homolog 2, Eyes absent homolog 3, Protein phosphatase 1D, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, Serine/threonine-protein phosphatase 4 catalytic subunit, Serine/threonine-protein phosphatase 5, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit