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PADI4 catalyses deimination at R26 position on H3. This activity inhibits the methylation of these residues by CARM1 thus causing transcriptional repression of target genes (PMID: 15339660).

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H3R26ci infosheet
Modified variants Histone H3.1, Histone H3.2, Histone H3.3
Writer/s Protein-arginine deiminase type-4
Disease associationsNo disease associations known for H3R26ci

Sites of arginine citrullination H2AR3ci, H3R17ci, H3R26ci, H3R2ci, H3R8ci, H4R3ci