Notice: Undefined variable: row0 in /var/home/coee/public_html/histome/ptm_sp.php on line 49

PADI4 catalyses deimination at R2 position on H3. This activity inhibits the methylation of these residues by CARM1 thus causing transcriptional repression of target genes (PMID: 15339660).

Download table as Excel
H3R2ci infosheet
Modified variants Histone H3.1, Histone H3.2, Histone H3.3
Writer/s Protein-arginine deiminase type-4
Disease associations
Inflammatory disease: Multiple sclerosis (MS); PMID: 17079667

Sites of arginine citrullination H2AR3ci, H3R17ci, H3R26ci, H3R2ci, H3R8ci, H4R3ci