E3 ubiquitin-protein ligase RING1
RING1 is a part of the human polycomb repressive complex 1-like (hPRC1L) complex that mediates ubiquitination of H2A lysine 119(PMID: 15386022).
| UniprotKB Accession | Q06587 |
|---|---|
| Alternative Name(s) | Polycomb complex protein RING1, RING finger protein 1, Really interesting new gene 1 protein |
| Writer for PTM/s | H2AK119ub |
| EC number | 6.3.2.- |
| No. of coding genes | E3 ubiquitin-protein ligase RING1 is coded by following 1 non-allelic gene/s |
| Gene name | ring finger protein 1 |
| Gene symbol | RING1 |
| Promoter region (-700 TSS +300) | Get sequence |
| Previous Symbol/s | |
| Aliases | RNF1 |
| GeneID | 6015 |
| Chromosomal location | 6p21.3 |
| HGNC | 10018 |
| Unigene | Hs.631989 |
| MIM | 602045 |
| RefSeq mRNA | NM_002931.3 |
| RefSeq Protein | NP_002922.2 |
| Disease associations | No disease associations known for E3 ubiquitin-protein ligase RING1 |
Lysine ubiquitinases E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, E3 ubiquitin-protein ligase DTX3L, E3 ubiquitin-protein ligase HUWE1, E3 ubiquitin-protein ligase RBX1, E3 ubiquitin-protein ligase RING1, E3 ubiquitin-protein ligase RING2, E3 ubiquitin-protein ligase RNF168, E3 ubiquitin-protein ligase RNF8, E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UHRF1, V(D)J recombination-activating protein 1