H3T45ph
H3T45 phosphorylation induces structural change within the nucleosome to facilitate DNA nicking and/or fragmentation linking its role to apoptosis (PMID: 19363025).
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| Modified variants | Histone H3.1, Histone H3.2, Histone H3.3 |
|---|---|
| Writer/s | Protein kinase C delta type |
| Eraser/s | |
| Disease associations | No disease associations known for H3T45ph |
Sites of serine/threonine/tyrosine phosphorylation H1S171ph, H1S172ph, H1S17ph, H1S186ph, H1S188ph, H1S26ph, H1T10ph, H1T137ph, H1T145ph, H1T153ph, H1T154ph, H1T17ph, H1T30ph, H2AS137ph, H2AS139ph, H2AS1ph, H2AT120ph, H2AY142ph, H2BS14ph, H3S10ph, H3S28ph, H3S31ph, H3S6ph, H3T11ph, H3T3ph, H3T45ph, H3T6ph, H3Y41ph, H4S1ph