H3Y41ph
Phosphorylation of H3 Tyrosine 41 by JAK2 prevents binding of Heterochromatin protein 1 alpha (HP1 alpha) to hematopoietic oncogene lmo2 promoter which is implicated in leukaemogenesis.(PMID: 19783980).
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| Modified variants | Histone H3.1, Histone H3.2, Histone H3.3 |
|---|---|
| Writer/s | Tyrosine-protein kinase JAK2 |
| Eraser/s | |
| Disease associations | No disease associations known for H3Y41ph |
Sites of serine/threonine/tyrosine phosphorylation H1S171ph, H1S172ph, H1S17ph, H1S186ph, H1S188ph, H1S26ph, H1T10ph, H1T137ph, H1T145ph, H1T153ph, H1T154ph, H1T17ph, H1T30ph, H2AS137ph, H2AS139ph, H2AS1ph, H2AT120ph, H2AY142ph, H2BS14ph, H3S10ph, H3S28ph, H3S31ph, H3S6ph, H3T11ph, H3T3ph, H3T45ph, H3T6ph, H3Y41ph, H4S1ph