Cyclin-dependent kinase 5

CDK5 has been shown to phosphorylate H1-derived peptides in vitro. Histone H1 proteins are often used as substrates in assays that determine the kinase activity of various cdks (PMID: 11741704).

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Cyclin-dependent kinase 5 infosheet
UniprotKB AccessionQ00535
Alternative Name(s)Cell division protein kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit (TPKII catalytic subunit)
Writer for PTM/s
EC number
No. of coding genesCyclin-dependent kinase 5 is coded by following 1 non-allelic gene/s
Gene namecyclin-dependent kinase 5
Gene symbolCDK5
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s
Chromosomal location7q36
RefSeq mRNANM_004935.3
RefSeq ProteinNP_004926.1
Disease associationsNo disease associations known for Cyclin-dependent kinase 5

Serine/threonine/tyrosine kinases Cyclin-dependent kinase 17, Cyclin-dependent kinase 3, Cyclin-dependent kinase 5, Death-associated protein kinase 3, DNA-dependent protein kinase catalytic subunit, Glycogen synthase kinase-3 beta, Inhibitor of nuclear factor kappa-B kinase subunit alpha, LIM domain kinase 2, Microtubule-associated serine/threonine-protein kinase-like, Mitogen-activated protein kinase kinase kinase 8, Mitogen-activated protein kinase kinase kinase MLT, Mitotic checkpoint serine/threonine-protein kinase BUB1, Protein kinase C beta type, Protein kinase C delta type, Ribosomal protein S6 kinase alpha-4, Ribosomal protein S6 kinase alpha-5, Serine-protein kinase ATM, Serine/threonine-protein kinase 10, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 4, Serine/threonine-protein kinase ATR, Serine/threonine-protein kinase haspin, Serine/threonine-protein kinase N1, Serine/threonine-protein kinase Nek6, Serine/threonine-protein kinase Nek9, Serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase tousled-like 1, Tyrosine-protein kinase BAZ1B, Tyrosine-protein kinase JAK2