Tyrosine-protein kinase BAZ1B

WSTF belongs to WAL protein family. It is part of an ATP-dependent chromatin remodelling machinery and is unique because it bears no homology to any other tyrosine kinase fold. WSTF phosphorylates H2A.X at tyrosine 142 during DNA damage responses (PMID: 19092802).

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Tyrosine-protein kinase BAZ1B infosheet
UniprotKB AccessionQ9UIG0
Alternative Name(s)Bromodomain adjacent to zinc finger domain protein 1B, Williams syndrome transcription factor, Williams-Beuren syndrome chromosomal region 10 protein, Williams-Beuren syndrome chromosomal region 9 protein, hWALp2
Writer for PTM/s H2AY142ph
EC number
No. of coding genesTyrosine-protein kinase BAZ1B is coded by following 1 non-allelic gene/s
Gene namebromodomain adjacent to zinc finger domain, 1B
Gene symbolBAZ1B
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/sWBSCR9, WBSCR10
Chromosomal location7q11.23
RefSeq mRNANM_032408.3
RefSeq ProteinNP_115784.1
Disease associationsNo disease associations known for Tyrosine-protein kinase BAZ1B

Serine/threonine/tyrosine kinases Cyclin-dependent kinase 17, Cyclin-dependent kinase 3, Cyclin-dependent kinase 5, Death-associated protein kinase 3, DNA-dependent protein kinase catalytic subunit, Glycogen synthase kinase-3 beta, Inhibitor of nuclear factor kappa-B kinase subunit alpha, LIM domain kinase 2, Microtubule-associated serine/threonine-protein kinase-like, Mitogen-activated protein kinase kinase kinase 8, Mitogen-activated protein kinase kinase kinase MLT, Mitotic checkpoint serine/threonine-protein kinase BUB1, Protein kinase C beta type, Protein kinase C delta type, Ribosomal protein S6 kinase alpha-4, Ribosomal protein S6 kinase alpha-5, Serine-protein kinase ATM, Serine/threonine-protein kinase 10, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 4, Serine/threonine-protein kinase ATR, Serine/threonine-protein kinase haspin, Serine/threonine-protein kinase N1, Serine/threonine-protein kinase Nek6, Serine/threonine-protein kinase Nek9, Serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase tousled-like 1, Tyrosine-protein kinase BAZ1B, Tyrosine-protein kinase JAK2