LIM domain kinase 2
It belongs to TKL Ser/Thr protein kinase family and is shown to phosphorylate histones in vitro (PMID: 8537403).
| UniprotKB Accession | P53671 | ||
|---|---|---|---|
| Alternative Name(s) | |||
| Writer for PTM/s | |||
| EC number | 2.7.11.1 | ||
| No. of coding genes | LIM domain kinase 2 is coded by following 1 non-allelic gene/s | ||
| Gene name | LIM domain kinase 2 | ||
| Gene symbol | LIMK2 | ||
| Promoter region (-700 TSS +300) | Get sequence | ||
| Previous Symbol/s | |||
| Aliases | |||
| GeneID | 3985 | ||
| Chromosomal location | 22q12 | ||
| HGNC | 6614 | ||
| Unigene | Hs.474596 | ||
| MIM | 601988 | ||
| RefSeq mRNA | NM_001031801.1 | NM_005569.3 | NM_016733.2 |
| RefSeq Protein | NP_001026971.1 | NP_005560.1 | NP_057952.1 |
| Disease associations | No disease associations known for LIM domain kinase 2 | ||
Serine/threonine/tyrosine kinases Cyclin-dependent kinase 17, Cyclin-dependent kinase 3, Cyclin-dependent kinase 5, Death-associated protein kinase 3, DNA-dependent protein kinase catalytic subunit, Glycogen synthase kinase-3 beta, Inhibitor of nuclear factor kappa-B kinase subunit alpha, LIM domain kinase 2, Microtubule-associated serine/threonine-protein kinase-like, Mitogen-activated protein kinase kinase kinase 8, Mitogen-activated protein kinase kinase kinase MLT, Mitotic checkpoint serine/threonine-protein kinase BUB1, Protein kinase C beta type, Protein kinase C delta type, Ribosomal protein S6 kinase alpha-4, Ribosomal protein S6 kinase alpha-5, Serine-protein kinase ATM, Serine/threonine-protein kinase 10, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 4, Serine/threonine-protein kinase ATR, Serine/threonine-protein kinase haspin, Serine/threonine-protein kinase N1, Serine/threonine-protein kinase Nek6, Serine/threonine-protein kinase Nek9, Serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase tousled-like 1, Tyrosine-protein kinase BAZ1B, Tyrosine-protein kinase JAK2