LIM domain kinase 2

It belongs to TKL Ser/Thr protein kinase family and is shown to phosphorylate histones in vitro (PMID: 8537403).

Download table as Excel
LIM domain kinase 2 (LIMK-2) infosheet
UniprotKB AccessionP53671
Alternative Name(s)
Writer for PTM/s
EC number
No. of coding genesLIM domain kinase 2 is coded by following 1 non-allelic gene/s
Gene nameLIM domain kinase 2
Gene symbolLIMK2
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s
Chromosomal location22q12
RefSeq mRNANM_001031801.1NM_005569.3NM_016733.2
RefSeq ProteinNP_001026971.1NP_005560.1NP_057952.1
Disease associationsNo disease associations known for LIM domain kinase 2

Serine/threonine/tyrosine kinases Cyclin-dependent kinase 17, Cyclin-dependent kinase 3, Cyclin-dependent kinase 5, Death-associated protein kinase 3, DNA-dependent protein kinase catalytic subunit, Glycogen synthase kinase-3 beta, Inhibitor of nuclear factor kappa-B kinase subunit alpha, LIM domain kinase 2, Microtubule-associated serine/threonine-protein kinase-like, Mitogen-activated protein kinase kinase kinase 8, Mitogen-activated protein kinase kinase kinase MLT, Mitotic checkpoint serine/threonine-protein kinase BUB1, Protein kinase C beta type, Protein kinase C delta type, Ribosomal protein S6 kinase alpha-4, Ribosomal protein S6 kinase alpha-5, Serine-protein kinase ATM, Serine/threonine-protein kinase 10, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 4, Serine/threonine-protein kinase ATR, Serine/threonine-protein kinase haspin, Serine/threonine-protein kinase N1, Serine/threonine-protein kinase Nek6, Serine/threonine-protein kinase Nek9, Serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase tousled-like 1, Tyrosine-protein kinase BAZ1B, Tyrosine-protein kinase JAK2