Histone deacetylase 10
HDAC10 belongs to the Class IIb histone deacetylase group (PMID: 18292778). It is involved in the alteration of reactive oxygen species (ROS) signaling via downregulation of TXNIP in human gastric cancers (PMID: 20680488). Also involved in the regulation of melanogenesis (PMID: 20032463).
| UniprotKB Accession | Q969S8 |
|---|---|
| Alternative Name(s) | |
| Eraser for PTM/s | |
| EC number | 3.5.1.98 |
| No. of coding genes | Histone deacetylase 10 is coded by following 1 non-allelic gene/s |
| Gene name | histone deacetylase 10 |
| Gene symbol | HDAC10 |
| Promoter region (-700 TSS +300) | Get sequence |
| Previous Symbol/s | |
| Aliases | DKFZP761B039 |
| GeneID | 83933 |
| Chromosomal location | 22q13.31 |
| HGNC | 18128 |
| Unigene | Hs.26593 |
| MIM | 608544 |
| RefSeq mRNA | NM_032019.5 |
| RefSeq Protein | NP_114408.3 |
| Disease associations | No disease associations known for Histone deacetylase 10 |
Lysine deacetylases Histone deacetylase 1, Histone deacetylase 10, Histone deacetylase 11, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 4, Histone deacetylase 5, Histone deacetylase 6, Histone deacetylase 7, Histone deacetylase 8, Histone deacetylase 9, NAD-dependent deacetylase sirtuin-1, NAD-dependent deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-3, mitochondrial, NAD-dependent deacetylase sirtuin-6