Lysine-specific demethylase 3B
KDM3B belongs to the JHDM2 family of demethylases and catalyses the demethylation of H3K9 mono and dimethylated forms (PMID: 16603237).
| UniprotKB Accession | Q7LBC6 |
|---|---|
| Alternative Name(s) | JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA |
| Eraser for PTM/s | H3K9me1, H3K9me2 |
| EC number | 1.14.11.- |
| No. of coding genes | Lysine-specific demethylase 3B is coded by following 1 non-allelic gene/s |
| Gene name | lysine (K)-specific demethylase 3B |
| Gene symbol | KDM3B |
| Promoter region (-700 TSS +300) | Get sequence |
| Previous Symbol/s | C5orf7, JMJD1B |
| Aliases | KIAA1082, NET22 |
| GeneID | 51780 |
| Chromosomal location | 5q31 |
| HGNC | 1337 |
| Unigene | Hs.483486 |
| MIM | 609373 |
| RefSeq mRNA | NM_016604.3 |
| RefSeq Protein | NP_057688.2 |
| Disease associations | Hematological disorder: Mylodysplastic syndrome; PMID: 21536236 |
Lysine demethylases Histone lysine demethylase PHF8, Lysine-specific demethylase 2A, Lysine-specific demethylase 2B, Lysine-specific demethylase 3A, Lysine-specific demethylase 3B, Lysine-specific demethylase 4A, Lysine-specific demethylase 4B, Lysine-specific demethylase 4C, Lysine-specific demethylase 4D, Lysine-specific demethylase 5A, Lysine-specific demethylase 5B, Lysine-specific demethylase 5C, Lysine-specific demethylase 5D, Lysine-specific demethylase 6A, Lysine-specific demethylase 6B, Lysine-specific demethylase 7, Lysine-specific demethylase 8, Lysine-specific demethylase NO66, Lysine-specific histone demethylase 1A, Lysine-specific histone demethylase 1B