N-acetyltransferase 10
Nat10 contains the N-acetyltrasferase domain and is found to acetylate free histones in vitro (PMID: 14592445). Nat10 is shown to be induces by DNA damage response (PMID: 17180247). It is also involved in the regulation of telomerase activity (PMID: 18082603).
| UniprotKB Accession | Q9H0A0 | |
|---|---|---|
| Alternative Name(s) | ||
| Writer for PTM/s | ||
| EC number | 2.3.1.- | |
| No. of coding genes | N-acetyltransferase 10 is coded by following 1 non-allelic gene/s | |
| Gene name | N-acetyltransferase 10 (GCN5-related) | |
| Gene symbol | NAT10 | |
| Promoter region (-700 TSS +300) | Get sequence | |
| Previous Symbol/s | ||
| Aliases | hALP, FLJ10774, FLJ12179, NET43 | |
| GeneID | 55226 | |
| Chromosomal location | 11p13 | |
| HGNC | 29830 | |
| Unigene | Hs.577281 | |
| MIM | 609221 | |
| RefSeq mRNA | NM_001144030.1 | NM_024662.2 |
| RefSeq Protein | NP_001137502.1 | NP_078938.2 |
| Disease associations | No disease associations known for N-acetyltransferase 10 | |
Lysine acetyltransferases Bifunctional protein NCOAT, Chromodomain Y-like protein, Circadian locomoter output cycles protein kaput, CREB-binding protein, Elongator complex protein 3, General transcription factor 3C polypeptide 4, Histone acetyltransferase KAT2A, Histone acetyltransferase KAT2B, Histone acetyltransferase KAT5, Histone acetyltransferase MYST2, Histone acetyltransferase MYST3, Histone acetyltransferase MYST4, Histone acetyltransferase p300, Histone acetyltransferase type B catalytic subunit, N-acetyltransferase 10, Nuclear receptor coactivator 1, Nuclear receptor coactivator 3, Probable histone acetyltransferase MYST1, Testis-specific chromodomain protein Y 1