Notice: Undefined variable: row0 in /var/home/coee/public_html/histome/ptm_sp.php on line 49

Histone H3K14 acetylation is critical for the recruitment of TFIID at the IFN-gamma locus and hence important for eliciting proper immune response (PMID: 12419248). In mice, acetylation by CLOCK at H3 Lys-14, is thought to initiate chromatin remodelling by inducing a transcription-permissive state (PMID: 16678094).

Download table as Excel
H3K14ac infosheet
Modified variants Histone H3.1, Histone H3.1t, Histone H3.2, Histone H3.3
Writer/s Bifunctional protein NCOAT, Circadian locomoter output cycles protein kaput, General transcription factor 3C polypeptide 4, Histone acetyltransferase KAT2A, Histone acetyltransferase MYST3
Disease associationsNo disease associations known for H3K14ac

Sites of lysine acetylation H1K25ac, H2AK5ac, H2AK9ac, H2BK120ac, H2BK12ac, H2BK15ac, H2BK16ac, H2BK20ac, H2BK46ac, H2BK5ac, H3K14ac, H3K18ac, H3K23ac, H3K27ac, H3K36ac, H3K4ac, H3K56ac, H3K9ac, H4K12ac, H4K16ac, H4K5ac, H4K8ac, H4K91ac