Notice: Undefined variable: row0 in /var/home/coee/public_html/histome/ptm_sp.php on line 49

Methylation of histone H3K4 is linked to active transcription (PMID: 15123803, PMID: 11498594). H3K4 methylation by MLL is shown to be involved in the activation of Hox gene cluster (PMID: 12453418).

Download table as Excel
H3K4me1 infosheet
Modified variants Histone H3.1, Histone H3.2, Histone H3.3
Writer/s Histone-lysine N-methyltransferase SETD7
Eraser/s Lysine-specific histone demethylase 1A
Disease associations
Metabolic disorder: Diabetes; PMID: 18809715

Sites of lysine methylation H1K186me1, H1K25me1, H2BK5me1, H3K27me1, H3K27me2, H3K27me3, H3K36me1, H3K36me2, H3K36me3, H3K4me1, H3K4me2, H3K4me3, H3K79me1, H3K79me2, H3K79me3, H3K9me1, H3K9me2, H3K9me3, H4K20me1, H4K20me2, H4K20me3