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H4K20 methylation status (mono- or di-) contributes to chromosome behaviour during mitosis and proper cytokinesis (PMID: 15200950).

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H4K20me2 infosheet
Modified variants Histone H4
Writer/s Histone-lysine N-methyltransferase SETD8, Histone-lysine N-methyltransferase SUV420H1, Histone-lysine N-methyltransferase SUV420H2, Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific
Disease associationsNo disease associations known for H4K20me2

Sites of lysine methylation H1K186me1, H1K25me1, H2BK5me1, H3K27me1, H3K27me2, H3K27me3, H3K36me1, H3K36me2, H3K36me3, H3K4me1, H3K4me2, H3K4me3, H3K79me1, H3K79me2, H3K79me3, H3K9me1, H3K9me2, H3K9me3, H4K20me1, H4K20me2, H4K20me3