H3K27me1
H3K27me1 signals are shown to be higher at active promoters than silent promoters, particularly downstream of the Transcription Start Site (TSS) (PMID: 17512414). Some reports argue that this site is dynamic since it is distributed throughout the euchromatic regions but is found to be depleted in the region surrounding the TSS (PMID: 17030614).
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| Modified variants | Histone H3.1, Histone H3.2, Histone H3.3 |
|---|---|
| Writer/s | Histone-lysine N-methyltransferase EZH1, Histone-lysine N-methyltransferase EZH2, Histone-lysine N-methyltransferase, H3 lysine-9 specific 3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 |
| Eraser/s | |
| Disease associations | No disease associations known for H3K27me1 |
Sites of lysine methylation H1K186me1, H1K25me1, H2BK5me1, H3K27me1, H3K27me2, H3K27me3, H3K36me1, H3K36me2, H3K36me3, H3K4me1, H3K4me2, H3K4me3, H3K79me1, H3K79me2, H3K79me3, H3K9me1, H3K9me2, H3K9me3, H4K20me1, H4K20me2, H4K20me3